Macular Hole Causes: What Triggers This Eye Condition

Noticing that straight lines have started to look bent, or that the centre of your vision seems slightly off, can be unsettling. One possible explanation is a macular hole: a small but significant break in the macula, the part of the retina that handles your sharpest, most detailed central vision.

This article breaks down macular hole causes in detail, who tends to be affected, and what generally happens once one is found.

Quick Overview

A macular hole forms when traction from the vitreous gel pulls on the macula until a small break opens up.
Age over 60, being female, high myopia, and previous eye trauma are the main risk factors.
Early signs include distorted central vision and straight lines appearing wavy, while side vision stays normal.
Vitrectomy surgery with a gas bubble is the common treatment, with meaningful improvement seen once the hole closes.

The sections below walk through the underlying mechanism, the groups more likely to be affected, what to watch for, and how treatment generally proceeds.

The Underlying Mechanism Behind a Macular Hole

A macular hole is a distinct condition from age-related macular degeneration, even though both affect central vision in similar ways. To understand why a macular hole forms specifically, it helps to know what the vitreous gel actually does inside the eye. The vitreous cavity is filled with a clear, gel-like substance, sometimes described as a jelly-like substance, that gives the eyeball its shape and sits directly against the retinal surface.

Why the vitreous changes with age

In younger eyes, the vitreous gel is firmly attached to the retina, including the macula, the central part responsible for fine detail. As the years pass, this gel naturally becomes thinner and more watery. It gradually separates from the back of the eye in a process called posterior vitreous detachment, something nearly everyone experiences to some degree.

For the vast majority of people, this separation happens without consequence. A short period of floaters or flashes is common, and nothing more comes of it.

When the separation does not happen evenly

The trouble starts when part of the vitreous gel stays stuck to the macula while the rest pulls free. This uneven separation creates a pulling force, often described as traction, directly on the macular tissue. Research on this process confirms that vitreous pulls away from retina tissue unevenly in some people, and over time, this traction is what causes a macular hole to open up, beginning with a small break in the macula that can widen if left unaddressed.

Causes beyond ageing

Not every macular hole forms through this slow, age-related traction process. Eye trauma, such as a direct impact, can cause a macular hole to develop suddenly rather than gradually, sometimes in younger individuals who would not otherwise be affected by vitreous changes.

A macula hole can also develop as a result of other underlying eye diseases. Conditions including retinal detachment, macular pucker, longstanding eye inflammation affecting the macula, and diabetic retinopathy have all been linked to secondary macular hole formation. Diabetes, high myopia, and inflammation of the eye are generally recognised as contributors to secondary macular hole development, separate from the more common age-related traction process described above.

Who Tends to Develop a Macular Hole

Certain groups are more likely to be affected, though none of these factors means a hole will definitely form.

Adults over 60 make up the majority of cases, which lines up directly with the natural ageing of the vitreous gel described above. Women are affected at a notably higher rate than men, a pattern seen consistently across studies even though the precise reason remains unclear.

High myopia, meaning a strong short-sighted prescription, adds further risk. A highly myopic eye is physically longer than average, which thins and stretches the retina and places extra strain on the macula over time.

If a macular hole has already developed in one eye, the other eye carries a higher chance of developing one too, which is why ongoing monitoring of both eyes matters after a diagnosis. Blood vessels affected by long-term diabetes, prior retinal surgery, and chronic eye inflammation are additional factors worth raising with your eye specialist.

Recognising the Early Signs

Symptoms of a macular hole are specific to central vision. Peripheral or side vision is not affected, since the macula only governs the central part of the visual field.

In the early stages, straight-ahead vision often shifts subtly first, with distorted vision being one of the earliest clues that something has changed. Door frames, window edges, or lines of text may begin to look slightly wavy or warped rather than straight. Fine detail becomes harder to make out, and small print that was once easy to read may start to blur or distort.

As the hole is a small but progressively larger break in the macula over time, this distortion can develop into a blurred or blank patch sitting directly in the centre of your visual field. Everyday tasks relying on sharp central vision, such as reading, recognising faces, or threading a needle, tend to become noticeably more difficult.

A sudden, sharp change in central vision, especially alongside a sudden rise in floaters or flashes of light, calls for immediate medical attention. These combined symptoms can point toward retinal detachment, a separate and urgent condition.

How a Macular Hole Is Diagnosed and Treated

A macular hole is diagnosed through a comprehensive eye examination using optical coherence tomography, a detailed, non-invasive scan that produces a cross-sectional image of the retina. This scan shows exactly how large and how deep the break in the macula is. Once a macular hole is diagnosed, this imaging is what determines how it is treated from that point forward.

Very small holes caught early are sometimes simply monitored rather than treated immediately. For holes affecting vision more significantly, vitrectomy surgery is the standard surgical procedure. Performed under local anaesthetic, this surgery removes the vitreous gel responsible for the traction and replaces it with a gas bubble.

A face-down position is often recommended for several days afterwards, helping the gas bubble stay in steady contact with the macula while it heals. A Cochrane review confirms that face-down posture aids healing for larger holes specifically, though the evidence for smaller holes is less clear-cut. Over the following weeks, the gas bubble dissolves on its own as natural fluid produced by the eye gradually fills the space, with air pressure inside the eye adjusting as this happens.

Most patients notice a real improvement in central vision once the hole has closed, though how a macular hole depends on its size and duration before surgery affects how much vision recovery actually occurs. A second operation is occasionally needed if the initial surgery does not fully close the hole, though this applies to a minority of cases.

When You Should See an Eye Specialist

Any sudden or rapid change in your central vision deserves a prompt assessment rather than a wait-and-see approach. A macular hole on its own does not usually cause pain, which means changes in your vision are often the only clue something is wrong. About half of those who experience traction-related changes in one eye go on to develop similar changes in the other eye, so attending scheduled reviews matters even after one eye has been treated.

Notice a Change in Your Central Vision?

A thorough eye examination, including optical coherence tomography where needed, gives you clarity on what is happening and what comes next. The sooner a macular hole is assessed, the more options generally remain open. The team at Armadale Eye Clinic can examine your retina in detail, explain your results clearly, and walk you through the right next steps based on your individual situation.

To book a consultation regarding macular holes or other retinal conditions, please call us on (03) 9070 5753.

Frequently Asked Questions

Will my vision return to completely normal after macular hole surgery?

Closing the hole does not always mean your vision returns to exactly how it was beforehand. Some patients are left with mild residual distortion or a slightly reduced level of detail even after a successful closure. This is more likely if the hole was large or had been present for an extended period before surgery. Your eye specialist can talk you through what a realistic outcome looks like based on your individual scan.

Can stress or screen use cause a macular hole?

No clinical evidence links stress, screen time, or visual strain to the development of a macular hole. The condition is driven by mechanical traction from the vitreous gel, by trauma, or by an underlying eye disease, not by lifestyle factors related to eye use. If you are experiencing visual symptoms and are concerned about screen use specifically, it is still worth having your eyes examined to rule out other causes.

How quickly does a macular hole usually get worse if left untreated?

Progression speed varies considerably between individuals. Some macular holes remain stable or progress very slowly over months, while others enlarge more quickly and affect vision sooner. Because this pattern is unpredictable, regular monitoring by an eye specialist after a macular hole is first detected is the only reliable way to track how it is progressing.

Can I fly while the gas bubble is still in my eye?

No, flying or travelling to high altitude is not safe while the gas bubble is present in your eye. Changes in air pressure during the flight can cause the bubble to expand, leading to a dangerous and sudden rise in eye pressure. Your eye specialist will confirm once the bubble has dissolved enough for air travel to be safe again, which is usually several weeks after surgery.

Any surgical or invasive procedure carries risks. Before proceeding, you should seek a second opinion from an appropriately qualified health practitioner.

References

https://my.clevelandclinic.org/health/diseases/14208-macular-hole

https://www.sciencedirect.com/science/article/pii/S003962579700132X